SCHEMBL2278808

SCHEMBL2278808

COCC(c1ccc(Cl)cc1)C(COC)c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.47
SLC6A3 Q01959 3/20 0.47
SLC6A2 P23975 2/20 0.47
AOC3 Q16853 2/20 0.43
ADRB2 P07550 1/20 0.43
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
HIF1A Q16665 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALOX15 P16050 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL813184 0.82 SLC6A4 (0.47) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL436859 0.80 ADRB2 (0.46) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL1155411 0.78 AOC3 (0.52) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL31737779 0.78 AOC3 (0.58) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL5462262 0.78 SCN4A (0.53) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL5460859 0.78 SCN4A (0.53) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL2270719 0.77 AOC3 (0.43) SLC6A4SLC6A3SLC6A2AOC3LMNA
SCHEMBL7113377 0.75 AOC3 (0.42) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL28428096 0.74 SLC6A4 (0.41) SLC6A4SLC6A3SLC6A2AOC3ADRB2
SCHEMBL391965 0.72 ADRB2 (0.48) SLC6A4SLC6A3SLC6A2AOC3ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
EP-1647575-B1 POLYPROPYLENE RESIN COMPOSITION PRIME POLYMER CO LTD (JP) 2009-07-29 EP disclosed
EP-1270647-B1 BRANCHED POLYOLEFIN, PROCESS FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING BRANCHED POLYOLEFIN MITSUI CHEMICALS INC (JP) 2009-07-01 EP disclosed
US-20090043050-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2009-02-12 US disclosed
US-7488789-B2 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-02-10 US disclosed
EP-0585869-A1 Solid titanium catalyst component for olefin polymerization, process for preparing the same, catalyst for olefin polymerization and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-09 EP disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
US-4971937-A COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS HIMONT INCORPORATED (US) 1990-11-20 US disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed
EP-0361494-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-04 EP disclosed