Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901097 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MAPTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL11343217 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAHSD17B10KMT2A | |
| SCHEMBL11888024 | 0.70 | HPGD (0.44) | ALDH1A1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL22774477 | 0.69 | GRIN2C (0.41) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL22774982 | 0.67 | GAA (0.49) | ALDH1A1MAPTLMNAKDM4EHSD17B10 | |
| SCHEMBL6902092 | 0.65 | GRIN2C (0.35) | ALDH1A1HSD17B10SMN1; SMN2GAACYP1A2 | |
| SCHEMBL15107088 | 0.65 | MAPK1 (0.35) | ALDH1A1LMNAHSD17B10HPGDKMT2A | |
| SCHEMBL3784658 | 0.64 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNAHSD17B10GAA | |
| SCHEMBL9980122 | 0.63 | MAPK1 (0.42) | ALDH1A1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL22774673 | 0.61 | GABRA1 (0.41) | ALDH1A1GAACYP1A2CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249664-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |