SCHEMBL2278950

SCHEMBL2278950

CCCCO[Si](CC(F)C(F)F)(OCCCC)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2286910 0.89
SCHEMBL4733023 0.82 ADRB2 (0.35) ADRB2ADRB1ADRB3ATM
SCHEMBL2398601 0.77 ADRB2 (0.35) ADRB2ADRB1ADRB3ATM
SCHEMBL191963 0.77
SCHEMBL8768092 0.76
SCHEMBL820459 0.74 OPRM1 (0.39) ADRB2ADRB1ADRB3ATM
SCHEMBL7692660 0.74 ADRB2 (0.32) ADRB2ADRB1ADRB3ATM
SCHEMBL17076451 0.74 ADRB2 (0.32) ADRB2ADRB1ADRB3ATM
SCHEMBL17076454 0.72 ADRB2 (0.31) ADRB2ADRB1ADRB3
SCHEMBL3686619 0.72 ATM (0.33) ADRB2ADRB1ADRB3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356084-B2 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL CHEMICALS INT BV (NL) 2018-05-23 EP disclosed
EP-2356084-B1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL NV (NL) 2014-07-23 EP disclosed
US-8703874-B2 Powder to hydrophobise and its use CELANESE SWITZERLAND AG (CH) 2014-04-22 US disclosed
US-20110203487-A1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL N.V. (NL) 2011-08-25 US disclosed