Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.44 |
| ▸ | BRD1 | O95696 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790088 | 1.00 | NR4A2 (0.46) | NR4A2BRPF1BRD1BRD4BRPF3 | |
| SCHEMBL22789951 | 1.00 | NR4A2 (0.46) | NR4A2BRPF1BRD1BRD4BRPF3 | |
| SCHEMBL22790093 | 0.82 | NR4A2 (0.52) | NR4A2BRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL18245084 | 0.79 | ALDH1A1 (0.46) | BRPF1BRD1BRD4BRPF3MEN1 | |
| SCHEMBL18245086 | 0.79 | ALDH1A1 (0.46) | BRPF1BRD1BRD4BRPF3MEN1 | |
| SCHEMBL22790352 | 0.78 | NR4A2 (0.48) | NR4A2BRD4MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29646078 | 0.78 | RAD52 (0.45) | BRPF1BRD1BRD4BRPF3MEN1 | |
| SCHEMBL22790174 | 0.77 | NR4A2 (0.47) | NR4A2BRPF1BRD4MEN1KMT2A | |
| SCHEMBL22789981 | 0.77 | NR4A2 (0.49) | NR4A2BRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL22790260 | 0.77 | NR4A2 (0.46) | NR4A2BRPF1BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |