Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 0.48 |
| ▸ | KHK | P50053 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790093 | 0.95 | NR4A2 (0.52) | NR4A2KHKMEN1KMT2AKDM4E | |
| SCHEMBL22790131 | 0.83 | SIRT6 (0.56) | NR4A2KHKMEN1KMT2AKDM4E | |
| SCHEMBL22790260 | 0.83 | NR4A2 (0.46) | NR4A2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL22790174 | 0.81 | NR4A2 (0.47) | NR4A2KHKMEN1KMT2AKDM4E | |
| SCHEMBL1096244 | 0.81 | NR4A2 (0.51) | NR4A2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL22790129 | 0.79 | NR4A2 (0.49) | NR4A2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL22790088 | 0.78 | NR4A2 (0.46) | NR4A2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL22789951 | 0.78 | NR4A2 (0.46) | NR4A2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL22790239 | 0.78 | MEN1 (0.43) | NR4A2KHKMEN1KMT2AKDM4E | |
| SCHEMBL22790343 | 0.77 | KHK (0.46) | KHKHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |