Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174169 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRTHRB | |
| SCHEMBL12590416 | 0.85 | MEN1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23473535 | 0.84 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL22788846 | 0.84 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL14177531 | 0.83 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL16174165 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBPLA2G2C | |
| SCHEMBL19508497 | 0.79 | PLA2G2C (0.54) | PLA2G2C | |
| SCHEMBL23473527 | 0.77 | NOS3 (0.32) | — | |
| SCHEMBL8164719 | 0.76 | — | — | |
| SCHEMBL19546005 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178597-A1 | ANTIBODIES COMPRISING SITE-SPECIFIC GLUTAMINE TAGS, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2021-09-10 | — | — | WO | disclosed |
| WO-2020252015-A1 | IMMUNOMODULATOR ANTIBODY DRUG CONJUGATES AND USES THEREOF | SUTRO BIOPHARMA, INC. (US) | 2020-12-17 | — | — | WO | disclosed |