SCHEMBL2279059

SCHEMBL2279059

O=C1CC=CC2=C1Sc1ccccc1N2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.51
MAPT P10636 7/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
PABPC1 P11940 1/20 0.51
NPSR1 Q6W5P4 2/20 0.49
NOX1 Q9Y5S8 6/20 0.46
SNCA P37840 3/20 0.46
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
ALOX15 P16050 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX12 P18054 1/20 0.46
MAOA P21397 1/20 0.46
CNR1 P21554 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004464 0.81 KMT2A (0.38) GAAMAPTMEN1KMT2APABPC1
SCHEMBL6313583 0.81 NOX1 (0.46) GAAMAPTMEN1KMT2APABPC1
SCHEMBL10738447 0.80 GAA (0.42) GAAMAPTMEN1KMT2APABPC1
SCHEMBL11303789 0.78 NOX1 (0.43) GAAMAPTMEN1KMT2APABPC1
SCHEMBL3631017 0.78 MEN1 (0.31) GAAMAPTMEN1KMT2APABPC1
SCHEMBL1725699 0.78 MEN1 (0.33) GAAMAPTMEN1KMT2APABPC1
SCHEMBL31213291 0.74 MEN1 (0.36) GAAMAPTMEN1KMT2APABPC1
SCHEMBL2197848 0.74 MEN1 (0.36) GAAMAPTMEN1KMT2APABPC1
SCHEMBL12463182 0.71 L3MBTL1 (0.66) GAAMAPTMEN1KMT2APABPC1
SCHEMBL12462878 0.71 L3MBTL1 (0.66) GAAMAPTMEN1KMT2APABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228024-A1 NOVEL HYDRONAPHTALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND AstraZeneca AB (SE) 2002-08-07 EP claimed
WO-2001030734-A1 NOVEL HYDRONAPHTALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND ASTRAZENECA AB (SE) 2001-05-03 WO claimed
EP-0076266-B1 ELECTRODE FOR THE ELECTROCHEMICAL REGENERATION OF CO-ENZYME, A METHOD OF MAKING SAID ELECTRODE, AND THE USE THEREOF GORTON, Lo (SE) 1988-11-09 EP claimed
US-20250135451-A1 ELECTRODE CARTRIDGE AND DEVICE FOR THE DETECTION OF TOTAL VIABLE MICROORGANISMS (TVM), AND RELATED METHODS UNIVERSIDAD DE BUENOS AIRES (AR) 2025-05-01 US disclosed
CN-111448698-B Microbial power generation device and operation method thereof 栗田工业株式会社 2025-01-10 CN disclosed
WO-2024090562-A1 FAD-DEPENDENT GLUTAMATE DEHYDROGENASE キッコーマン株式会社 2024-05-02 WO disclosed
CN-111051364-B Epoxidized polyfarnesenes and methods for making the same 飞纳技术有限公司 2023-03-14 CN disclosed
CN-111051364-A Epoxidized polyfarnesenes and methods for making the same 飞纳技术有限公司 2020-04-21 CN disclosed
US-9829487-B2 Self-assembled monolayers and methods for using the same in biosensing applications NUTECH VENTURES (US) 2017-11-28 US disclosed
US-9337507-B2 Microbial power generator KURITA WATER INDUSTRIES LTD. (JP) 2016-05-10 US disclosed
US-9209475-B2 Method for microbially generating electricity and microbial power generator KURITA WATER INDUSTRIES LTD. (JP) 2015-12-08 US disclosed
WO-2003078646-A2 AZA-THIOXANTHENONES WITH ANTITUMOR ACTIVITY ALBANY MOLECULAR RESEARCH, INC. (US) 2003-09-25 WO disclosed
EP-1307179-A2 COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR AVOIDING SKIN DAMAGE CAUSED BY PEROXIDE BASF AKTIENGESELLSCHAFT (DE) 2003-05-07 EP disclosed
EP-1228024-A1 NOVEL HYDRONAPHTALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND AstraZeneca AB (SE) 2002-08-07 EP disclosed
WO-2002007698-A2 COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR AVOIDING SKIN DAMAGE CAUSED BY PEROXIDE BASF AKTIENGESELLSCHAFT (DE) 2002-01-31 WO disclosed
WO-2001030734-A1 NOVEL HYDRONAPHTALENE COMPOUNDS, PREPARED BY A RHODIUM CATALYZED RING OPENING REACTION IN THE PRESENCE OF PHOSPHINE LIGAND ASTRAZENECA AB (SE) 2001-05-03 WO disclosed
EP-0076266-B1 ELECTRODE FOR THE ELECTROCHEMICAL REGENERATION OF CO-ENZYME, A METHOD OF MAKING SAID ELECTRODE, AND THE USE THEREOF GORTON, Lo (SE) 1988-11-09 EP disclosed
EP-0134033-B1 BENZTHIAZINOPHENOXAZINE DYESTUFFS BAYER AG (DE) 1987-07-08 EP disclosed
EP-0134033-A1 Benzthiazinophenoxazine dyestuffs BAYER AG (DE) 1985-03-13 EP disclosed
US-3961055-A ANTIEMETIC AGENTS RHONE-POULENC INDUSTRIES (FR) 1976-06-01 US disclosed