SCHEMBL9004464

SCHEMBL9004464

Cc1ccc2c(c1)NC1=C(S2)C(=O)CC=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.38
MEN1 O00255 8/20 0.38
GAA P10253 6/20 0.38
MAPT P10636 6/20 0.38
MAPK13 O15264 1/20 0.38
DAPK3 O43293 1/20 0.38
ROCK2 O75116 1/20 0.38
CHEK2 O96017 1/20 0.38
PIM1 P11309 1/20 0.38
CDK2 P24941 1/20 0.38
RECQL P46063 1/20 0.38
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
CSNK2A1 P68400 1/20 0.38
PRKCZ Q05513 1/20 0.38
PRKAA1 Q13131 1/20 0.38
ROCK1 Q13464 1/20 0.38
DYRK1A Q13627 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2279059 0.81 GAA (0.51) KMT2AMEN1GAAMAPTNPSR1
SCHEMBL1725699 0.72 MEN1 (0.33) KMT2AMEN1GAAMAPTNPSR1
SCHEMBL10887804 0.70 KDM4E (0.40) KMT2AMEN1ATMKDM4EALDH1A1
SCHEMBL225814 0.69 NOX1 (0.47) KMT2AMEN1GAAMAPTEPHX2
SCHEMBL3631017 0.67 MEN1 (0.31) KMT2AMEN1GAAMAPTNPSR1
SCHEMBL225829 0.65 NOX1 (0.65) KMT2AMEN1GAAMAPTNPSR1
SCHEMBL2756476 0.63 NOX1 (0.53) KMT2AMEN1GAAMAPTEPHX2
SCHEMBL434490 0.63 EPHX2 (0.77) KMT2AGAAMAPTEPHX2MMP12
SCHEMBL10738447 0.63 GAA (0.42) KMT2AMEN1GAAMAPTNPSR1
SCHEMBL6313583 0.63 NOX1 (0.46) KMT2AMEN1GAAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500760-A Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1996-03-19 US disclosed
EP-0531143-A2 Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1993-03-10 EP disclosed