Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18499701 | 0.82 | MEN1 (0.31) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL21541167 | 0.80 | — | — | |
| SCHEMBL25491858 | 0.78 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL13126744 | 0.78 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19881271 | 0.78 | MEN1 (0.38) | MEN1CYP3A4ALOX15KMT2AALDH1A1 | |
| SCHEMBL19881206 | 0.75 | TGFBR1 (0.34) | ALDH1A1 | |
| SCHEMBL13126745 | 0.72 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL13126747 | 0.71 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL13126740 | 0.71 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL13126746 | 0.71 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252398-A1 | PROTEOLYSIS-TARGETING PROTACS INDUCING DEGRADATION OF C-MIC PROTEIN | NORTHWESTERN UNIVERSITY (US) | 2020-12-17 | — | — | WO | disclosed |