Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 5/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
| ▸ | CYBB | P04839 | 1/20 | 0.30 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18850696 | 0.84 | DPP4 (0.35) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL22906473 | 0.84 | DPP4 (0.35) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL20180742 | 0.82 | DPP4 (0.34) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL25819728 | 0.82 | DPP4 (0.35) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL23560142 | 0.81 | DRD2 (0.35) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL21106182 | 0.80 | KDM4E (0.37) | NCF1DPP4CHRNA7MAPK14 | |
| SCHEMBL22856476 | 0.80 | KDM4E (0.37) | NCF1DPP4CHRNA7MAPK14 | |
| SCHEMBL26464988 | 0.80 | NCF1 (0.33) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL23806873 | 0.80 | KDM4E (0.34) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL17586038 | 0.79 | CHRNA7 (0.38) | NCF1DPP4CHRNA7MAPK14DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192586-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2021011634-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| WO-2020251972-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020251971-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020251969-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |