Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791249 | 0.94 | BRD4 (0.37) | EPHX2PTGDR2SLC6A5KCNH2DRD4 | |
| SCHEMBL22776477 | 0.91 | PTGER4 (0.43) | EPHX2HCRTR1HCRTR2PTGDR2SLC6A5 | |
| SCHEMBL22776475 | 0.91 | PTGER4 (0.43) | EPHX2HCRTR1HCRTR2PTGDR2SLC6A5 | |
| SCHEMBL29526837 | 0.91 | PTGER4 (0.43) | EPHX2HCRTR1HCRTR2PTGDR2SLC6A5 | |
| SCHEMBL22791391 | 0.91 | HTR4 (0.42) | EPHX2BRD4 | |
| SCHEMBL22791366 | 0.88 | PTGDR2 (0.36) | EPHX2HCRTR1HCRTR2PTGDR2CCR2 | |
| SCHEMBL22791290 | 0.87 | PTGDR2 (0.41) | PTGDR2SLC6A5CCR2KCNH2DRD4 | |
| SCHEMBL22791289 | 0.87 | PTGDR2 (0.41) | PTGDR2SLC6A5CCR2KCNH2DRD4 | |
| SCHEMBL22791152 | 0.87 | PTGDR2 (0.41) | PTGDR2SLC6A5CCR2KCNH2DRD4 | |
| SCHEMBL22776479 | 0.85 | PTGER4 (0.43) | EPHX2HCRTR1HCRTR2SLC6A5DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |