Citric Acid

Citric Acid

SCHEMBL227914

O=C(O)CC(O)(CC(=O)O)C(=O)O.[Mo]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2

The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.41
ALDH1A1 P00352 2/20 0.94
HMGCR P04035 1/20 0.48
CHRM1 P11229 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
SLC13A5 Q86YT5 4/20 0.47
TSHR P16473 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
ACLY P53396 3/20 0.44
KDM4E B2RXH2 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
CPT2 P23786 2/20 0.42
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL29629071 1.00 ALDH1A1 (0.94) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL9299044 1.00 ALDH1A1 (0.94) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL664207 1.00 ALDH1A1 (0.94) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL27351508 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL28545110 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL28230623 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL5173630 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL9299268 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL5425793 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL1684053 0.97 ALDH1A1 (0.88) ALDH1A1HMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119976967-A Method for synthesizing metastable-phase molybdenum disulfide based on eutectic solvent and water system 北京化工大学 2025-05-13 CN claimed
EP-3400260-B2 SCAVENGER COMPOSITIONS FOR SULFUR SPECIES INNOPHOS INC (US) 2025-03-19 EP claimed
CN-118751156-A Spray pyrolysis system and application thereof 广东邦普循环科技有限公司 2024-10-11 CN claimed
CN-118496683-A Scavenger composition for sulfur species 伊诺弗斯公司 2024-08-16 CN claimed
US-11942643-B2 Doped sodium vanadium phosphate and preparation method and application thereof GUANGDONG BRUNP RECYCLING TECHNOLOGY CO., LTD. (CN) 2024-03-26 US claimed
US-20240038993-A1 DOPED SODIUM VANADIUM PHOSPHATE AND PREPARATION METHOD AND APPLICATION THEREOF GUANGDONG BRUNP RECYCLING TECHNOLOGY CO., LTD. (CN) 2024-02-01 US claimed
CN-114195193-B Doped sodium vanadium phosphate and preparation method and application thereof 广东邦普循环科技有限公司 2023-06-13 CN claimed
WO-2023071411-A1 DOPED SODIUM VANADIUM PHOSPHATE, PREPARATION METHOD THEREFOR AND USE THEREOF 广东邦普循环科技有限公司 2023-05-04 WO claimed
US-20230031548-A1 COMPOSITION FOR OPTIMIZED DIETARY SUPPLEMENT FORMULATIONS REDBUD BRANDS, LLC 2023-02-02 US claimed
CN-112175011-B Continuous preparation method of homogeneous organic molybdenum compound 中国石油化工股份有限公司 2022-09-27 CN claimed
CN-104091918-B Anode material for lithium-ion batteries and preparation method thereof 中信国安盟固利电源技术有限公司 2016-08-24 CN claimed
CN-103785414-B Hydrogenation of carboxylic acids catalyst, preparation method and application thereof SINOPEC CORP. (CN) 2016-03-30 CN claimed
CN-104585751-A Bathing agent WU JIANGXIAN 2015-05-06 CN claimed
CN-104091918-A Positive electrode material for lithium ion battery and preparation method of positive electrode material CITIC GUOAN MENGGULI POWER SOURCE TECHNOLOGY CO LTD 2014-10-08 CN claimed
CN-103785414-A Carboxylic acid hydrogenation catalyst, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2014-05-14 CN claimed
US-20120045538-A1 Nutrient team BLUMOFE ARI (US) 2012-02-23 US claimed
US-20090204187-A1 SOIL-BASED COMPOSITIONS AND METHODS FOR REMOVAL OF TOXINS FROM MAMMALS MANKOVITZ ROY J 2009-08-13 US claimed
CN-101376110-A Preparation of hydrogenation catalyst CHINA PETROCHEMICAL CO LTD (CN) 2009-03-04 CN claimed
US-20060233739-A1 TREATMENT OF MUCOCUTANEOUS DISORDERS THROUGH REVERSING CHRONIC IMFLAMMATION AND BARRIER DISRUPTION THORNFELDT CARL R 2006-10-19 US claimed
CN-1268719-C Method for preparing sulphur tail gas hydrogenation catalyst CHINA PETROLEUM & CHEMICAL (CN) 2006-08-09 CN claimed