Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.31 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.31 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667926 | 0.69 | TNF (0.35) | ALDH1A1HSD17B10PDPK1PARP1MAP3K11 | |
| SCHEMBL29941494 | 0.69 | EGFR (0.34) | ALDH1A1HSD17B10PDPK1PARP1MAP3K11 | |
| SCHEMBL20866823 | 0.63 | PIK3CD (0.46) | — | |
| SCHEMBL22791662 | 0.62 | ALDH1A1 (0.31) | ALDH1A1HSD17B10 | |
| SCHEMBL29467245 | 0.62 | LMNA (0.38) | ALDH1A1PDPK1PARP1MAP3K11TLK2 | |
| SCHEMBL5929534 | 0.60 | MAPT (0.40) | ALDH1A1HSD17B10MAPK1MAP3K11TLK2 | |
| SCHEMBL20855206 | 0.60 | ALDH1A1 (0.33) | ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL22025577 | 0.60 | KDM4E (0.33) | ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL20653883 | 0.60 | MAPT (0.52) | ALDH1A1MAPK1 | |
| SCHEMBL31416900 | 0.60 | CNOT7 (0.40) | ALDH1A1MAPK1PDPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252262-A1 | REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-17 | — | — | WO | disclosed |