Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087151 | 0.78 | — | — | |
| SCHEMBL3143437 | 0.75 | — | — | |
| SCHEMBL14905891 | 0.75 | — | — | |
| SCHEMBL28030824 | 0.74 | CCNC (0.33) | CCNCCDK8 | |
| SCHEMBL2562718 | 0.74 | PIK3CD (0.32) | PIK3CDCCNCCDK8 | |
| SCHEMBL27412666 | 0.74 | — | — | |
| SCHEMBL4062968 | 0.74 | — | — | |
| SCHEMBL22771465 | 0.74 | — | — | |
| SCHEMBL2050872 | 0.74 | — | — | |
| SCHEMBL1645972 | 0.73 | FAAH (0.40) | PIK3CDCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249791-A1 | SUBSTITUTED PYRAZOLO[4,3-b]PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |