SCHEMBL1645972

SCHEMBL1645972

C=CCC1CCN(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.40
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
PRSS1 P07477 2/20 0.34
CTRC Q99895 2/20 0.34
F2 P00734 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31
PIK3CD O00329 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18093606 0.89 NOS1 (0.41) FAAHNOS1NOS2CHRNB2CHRNB4
SCHEMBL2562718 0.82 PIK3CD (0.32) PIK3CDCCNCCDK8
SCHEMBL360776 0.77 FAAH (0.40) FAAHNOS1NOS2CHRNB2CHRNB4
SCHEMBL169033 0.77 CYP3A4 (0.44) FAAHNOS1NOS2CHRNB2CHRNB4
SCHEMBL4347452 0.77 NOS1 (0.36) FAAHNOS1NOS2CHRNB2CHRNB4
SCHEMBL26361631 0.76 FAAH (0.39) FAAHNOS1NOS2CHRNB2CHRNB4
SCHEMBL14905891 0.75
SCHEMBL3143437 0.75
SCHEMBL14483980 0.74 FAAH (0.35) FAAHNOS1NOS2CHRNB2CHRNB4
SCHEMBL28935775 0.74 GBA1 (0.41) FAAHALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220177785-A1 TREATING AND STEAM CRACKING A COMBINATION OF PLASTIC-DERIVED OIL AND USED LUBRICATING OILS TO PRODUCE HIGH-VALUE CHEMICALS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-06-09 US claimed
EP-3973037-A1 TREATING AND STEAM CRACKING A COMBINATION OF PLASTIC-DERIVED OIL AND USED LUBRICATING OILS TO PRODUCE HIGH-VALUE CHEMICALS SABIC Global Technologies, B.V. (NL) 2022-03-30 EP claimed
CN-113853418-A Treating and steam cracking a combination of plastic-derived oil and spent lubricating oil to produce high value chemicals 沙特基础全球技术有限公司 2021-12-28 CN claimed
WO-2020234679-A1 TREATING AND STEAM CRACKING A COMBINATION OF PLASTIC-DERIVED OIL AND USED LUBRICATING OILS TO PRODUCE HIGH-VALUE CHEMICALS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-11-26 WO claimed
EP-2373617-B1 MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES BASF SE (DE) 2015-02-25 EP claimed
CN-102307854-B Mixtures of itaconic acid or itaconic acid derivatives with primary amines for the preparation of 1, 3-and 1, 4-alkylmethylpyrrolidones BASF SE 2014-11-12 CN claimed
US-8796472-B2 Mixtures of itaconic acid or itaconic acid derivatives and primary amines for producing 1,3- and 1,4-alkyl methyl pyrrolidones BASF SE (DE) 2014-08-05 US claimed
CN-102307854-A Mixtures of itaconic acid or itaconic acid derivatives with primary amines for the preparation of 1, 3-and 1, 4-alkylmethylpyrrolidones BASF SE 2012-01-04 CN claimed
US-20110251119-A1 MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES BASF SE (DE) 2011-10-13 US claimed
JP-4664069-B2 2011-04-06 JP claimed
EP-1587905-A3 VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-12-14 EP claimed
JP-2005532348-A 2005-10-27 JP claimed
EP-1587905-A2 VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-10-26 EP claimed
EP-1511740-A1 PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-03-09 EP claimed
WO-2004063348-A2 VESICANT TREATMENT WITH PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2004-07-29 WO claimed
WO-2003101978-A1 PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2003-12-11 WO claimed
US-20220177785-A1 TREATING AND STEAM CRACKING A COMBINATION OF PLASTIC-DERIVED OIL AND USED LUBRICATING OILS TO PRODUCE HIGH-VALUE CHEMICALS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-06-09 US disclosed
EP-3973037-A1 TREATING AND STEAM CRACKING A COMBINATION OF PLASTIC-DERIVED OIL AND USED LUBRICATING OILS TO PRODUCE HIGH-VALUE CHEMICALS SABIC Global Technologies, B.V. (NL) 2022-03-30 EP disclosed
US-5453516-A Furanones, pyrrolidones BASF AKTIENGESELLSCHAFT (DE) 1995-09-26 US disclosed
EP-0602515-A1 Process for the preparation of 5-membered heterocycles BASF Aktiengesellschaft (DE) 1994-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251119-A1 MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES HADHA, HADH, ASS1 FAAH 677/4885NOS1 440/4885NOS2 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.