Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 7/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 2/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792321 | 0.92 | CCNT1 (0.38) | CCNT1PDCD1CD274CDK9IRAK1 | |
| SCHEMBL22792031 | 0.92 | CCNT1 (0.48) | CCNT1CDK9FYNCCNKKDR | |
| SCHEMBL22792629 | 0.81 | MEN1 (0.42) | CCNT1FYNPDE5A | |
| SCHEMBL12501667 | 0.75 | CCNT1 (0.44) | CCNT1PDCD1CD274CDK9IRAK1 | |
| SCHEMBL22792032 | 0.74 | EHMT2 (0.45) | CCNT1 | |
| SCHEMBL16040798 | 0.73 | CCNT1 (0.49) | CCNT1CDK9CCNKKDR | |
| SCHEMBL1192676 | 0.73 | CCNT1 (0.55) | CCNT1CDK9CCNKKDR | |
| SCHEMBL23759644 | 0.66 | HRH3 (0.34) | — | |
| SCHEMBL23759828 | 0.66 | PIM2 (0.36) | — | |
| SCHEMBL21138657 | 0.66 | IRAK1 (0.42) | CCNT1IRAK1TTKLRRK2TRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |