SCHEMBL2279291

SCHEMBL2279291

CC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)O[PH](=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.52
ALDH1A1 P00352 6/20 0.43
KMT2A Q03164 4/20 0.43
TSHR P16473 3/20 0.43
MEN1 O00255 3/20 0.43
MAPK1 P28482 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
BLM P54132 2/20 0.43
ATM Q13315 2/20 0.43
HIF1A Q16665 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
MAPT P10636 2/20 0.43
USP2 O75604 1/20 0.43
CYP2D6 P10635 1/20 0.43
GAA P10253 5/20 0.42
LMNA P02545 2/20 0.42
GMNN O75496 1/20 0.41
GABBR2 O75899 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2279290 0.89 HMGCR (0.54) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL2852665 0.85 HMGCR (0.50) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL7184451 0.85 HMGCR (0.50) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL10426639 0.77 HMGCR (0.65) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL5081887 0.77 TYR (0.41) HMGCRALDH1A1GAALMNACYP2C9
SCHEMBL2861240 0.76 HMGCR (0.52) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL10426640 0.76 HMGCR (0.63) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL27906237 0.75 GAA (0.48) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL39082 0.75 HMGCR (0.57) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL1278385 0.74 HMGCR (0.54) HMGCRALDH1A1KMT2ATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644749-A Polyisocyanate composition, aqueous coating composition and coated substrate 旭化成株式会社 2022-06-21 CN disclosed
CN-107207699-B Polyisocyanate composition, method for producing same, coating composition, aqueous coating composition, and coated substrate 旭化成株式会社 2021-03-16 CN disclosed
EP-3187565-B1 THERMAL STABILIZER COMPOSITION AND SYNTHETIC RESIN COMPOSITION COMPRISING SAME ADEKA CORP (JP) 2021-02-17 EP disclosed
US-10654990-B2 Thermal stabilizer composition and synthetic resin composition comprising same ADEKA CORPORATION (JP) 2020-05-19 US disclosed
US-20170253727-A1 THERMAL STABILIZER COMPOSITION AND SYNTHETIC RESIN COMPOSITION COMPRISING SAME ADEKA CORPORATION (JP) 2017-09-07 US disclosed
EP-3187565-A1 THERMAL STABILIZER COMPOSITION AND SYNTHETIC RESIN COMPOSITION COMPRISING SAME Adeka Corporation (JP) 2017-07-05 EP disclosed
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
EP-2261998-A1 SOLAR CELL SUBSTRATE AND SOLAR CELL The Nippon Synthetic Chemical Industry Co., Ltd. (JP) 2010-12-15 EP disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-20080292896-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-11-27 US disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-B1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed
EP-0334051-A2 Electron beam-curable composition for release material and process for preparation of release material SHOWA DENKO KABUSHIKI KAISHA (JP) 1989-09-27 EP disclosed
US-4528374-A Polyalkylpiperidines CIBA-GEIGY CORPORATION (US) 1985-07-09 US disclosed
US-4315859-A STABILIZES PROVIDE PHOTSTABILITY OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed