SCHEMBL2279290

SCHEMBL2279290

CC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)O[PH](=O)OC(C)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.54
ALDH1A1 P00352 6/20 0.44
KMT2A Q03164 4/20 0.44
TSHR P16473 3/20 0.44
MEN1 O00255 3/20 0.44
MAPK1 P28482 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BLM P54132 2/20 0.44
ATM Q13315 2/20 0.44
HIF1A Q16665 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MAPT P10636 2/20 0.44
USP2 O75604 1/20 0.44
CYP2D6 P10635 1/20 0.44
GAA P10253 5/20 0.44
LMNA P02545 2/20 0.44
GMNN O75496 1/20 0.42
GABBR2 O75899 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2279291 0.89 HMGCR (0.52) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL2852665 0.87 HMGCR (0.50) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL7184451 0.87 HMGCR (0.50) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL21402675 0.81 HMGCR (0.47) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL17090812 0.80 HMGCR (0.46) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL10426639 0.78 HMGCR (0.65) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL2861240 0.77 HMGCR (0.52) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL10426640 0.77 HMGCR (0.63) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL39082 0.76 HMGCR (0.57) HMGCRALDH1A1KMT2ATSHRMEN1
SCHEMBL1278385 0.76 HMGCR (0.54) HMGCRALDH1A1KMT2ATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
EP-2261998-A1 SOLAR CELL SUBSTRATE AND SOLAR CELL The Nippon Synthetic Chemical Industry Co., Ltd. (JP) 2010-12-15 EP disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
US-20090320910-A1 TRANSPARENT ELECTRODE SUBSTRATE FOR SOLAR CELL NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE, AND TECHNOLOGY (JP) 2009-12-31 US disclosed
EP-1614699-B9 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2009-12-16 EP disclosed
EP-2071633-A1 TRANSPARENT ELECTRODE SUBSTRATE FOR SOLAR CELL National Institute of Advanced Industrial Science and Technology (JP) 2009-06-17 EP disclosed
US-20090043050-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2009-02-12 US disclosed
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-18 US disclosed
US-20080306234-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080306219-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080292896-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-11-27 US disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-B1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST PPIA, PPOX, PTGES2 HMGCR 3058/4885ALDH1A1 3243/4885KMT2A 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.