Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22793374 | 0.84 | MAOB (0.39) | HTTSMN1; SMN2FOLH1CTSBPPARA | |
| SCHEMBL22793375 | 0.82 | HCAR2 (0.41) | HTTSMN1; SMN2FOLH1CTSBMAPT | |
| SCHEMBL22793544 | 0.82 | CTSL (0.43) | HTTSMN1; SMN2FOLH1CTSBMAPT | |
| SCHEMBL29051797 | 0.65 | HTT (0.47) | HTTSMN1; SMN2FOLH1CTSBMAPT | |
| SCHEMBL2717727 | 0.64 | TSHR (0.52) | HTTSMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4781157 | 0.64 | TSHR (0.52) | HTTSMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL20582042 | 0.64 | TSHR (0.52) | HTTSMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL20128491 | 0.64 | CTSB (0.43) | HTTSMN1; SMN2FOLH1CTSBMAPT | |
| SCHEMBL20128499 | 0.64 | CTSB (0.43) | HTTSMN1; SMN2FOLH1CTSBMAPT | |
| SCHEMBL22086824 | 0.64 | HTT (0.46) | HTTSMN1; SMN2FOLH1CTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251953-A1 | STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-17 | — | — | WO | disclosed |