SCHEMBL2279600

SCHEMBL2279600

CC(=O)OCC(OC(C)=O)C(OC(C)=O)C(C=O)OC(C)=O

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.68
ABCB1 P08183 1/20 0.41
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TSHR P16473 1/20 0.30
TRPV1 Q8NER1 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258998 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL6464207 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL8117010 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL60323 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL8587285 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
Ammonia Solution, Strong SCHEMBL17061382 0.98 TDP1 (0.66) TDP1ABCB1POLBMAPK1
SCHEMBL60713 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL13893402 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL421756 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL426635 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612172-B1 ANTICANCER COMPOUNDS GODAVARI BIOREFINERIES LTD (IN) 2025-04-09 EP disclosed
CN-117915786-A Agent for heart disease and method for improving heart disease 未来生物科学实验室株式会社 2024-04-19 CN disclosed
US-11680078-B2 Anticancer compounds GODAVARI BIOREFINERIES LTD. (IN) 2023-06-20 US disclosed
US-20230132332-A1 Green Methods of Carbohydrate Acetylation UNITED STATES DEPARTMENT OF ENERGY 2023-04-27 US disclosed
US-20220389046-A1 ANTICANCER COMPOUNDS GODAVARI BIOREFINERIES LIMITED 2022-12-08 US disclosed
US-11084843-B2 Anticancer compounds GODAVARI BIOREFINERIES LTD. (IN) 2021-08-10 US disclosed
EP-3612172-A2 ANTICANCER COMPOUNDS Godavari Biorefineries Ltd. (IN) 2020-02-26 EP disclosed
US-20190284222-A1 ANTICANCER COMPOUNDS GODAVARI BIOREFINERIES LTD. (IN) 2019-09-19 US disclosed
WO-2018193476-A2 ANTICANCER COMPOUNDS GODAVARI BIOREFINERIES LIMITED (IN) 2018-10-25 WO disclosed
US-20140162900-A1 METHOD FOR HIGH-THROUGHPUT SCREENING OF COMPOUNDS AND COMBINATIONS OF COMPOUNDS FOR DISCOVERY AND QUANTIFICATION OF ACTIONS, PARTICULARLY UNANTICIPATED THERAPEUTIC OR TOXIC ACTIONS, IN BIOLOGICAL SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-06-12 US disclosed
EP-1687035-A1 METHOD FOR HIGH-THROUGHPUT SCREENING OF COMPOUNDS AND COMBINATIONS OF COMPOUNDS FOR DISCOVERY AND QUANTIFICATION OF ACTIONS, PARTICULARLY UNANTICIPATED THERAPEUTIC OR TOXIC ACTIONS, IN BIOLOGICAL SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-08-09 EP disclosed
EP-1663319-A2 METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL The Regents of the University of California (US) 2006-06-07 EP disclosed
US-20050202406-A1 Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-09-15 US disclosed
WO-2005051434-A1 METHOD FOR HIGH-THROUGHPUT SCREENING OF COMPOUNDS AND COMBINATIONS OF COMPOUNDS FOR DISCOVERY AND QUANTIFICATION OF ACTIONS, PARTICULARLY UNANTICIPATED THERAPEUTIC OR TOXIC ACTIONS, IN BIOLOGICAL SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-06-09 WO disclosed
WO-2005033652-A2 METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-04-14 WO disclosed
WO-2005015155-A2 METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-17 WO disclosed
WO-2005009597-A2 METHODS FOR COMPARING RELATIVE FLUX RATES OF TWO OR MORE BIOLOGICAL MOLECULES IN VIVO THROUGH A SINGLE PROTOCOL THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-03 WO disclosed
US-20050019251-A1 Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-01-27 US disclosed
US-20030224420-A1 Method for isolating and measuring proliferation of long-term label retaining cells and stem cells CALIFORNIA UNIVERSITY OF THE REGENTS OF, THE 2003-12-04 US disclosed
WO-2003087314-A2 METHOD FOR ISOLATING AND MEASURING PROLIFERATION OF LONG-TERM LABEL RETAINING CELLS AND STEM CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284222-A1 ANTICANCER COMPOUNDS MKI67, CCNI, API5 TDP1 2695/4885ABCB1 74/4885POLB 1690/4885
US-20230132332-A1 Green Methods of Carbohydrate Acetylation PUF60, HDAC10, NAT10 TDP1 2977/4885ABCB1 4305/4885POLB 2890/4885
US-11680078-B2 Anticancer compounds MKI67, CCNI, API5 TDP1 2695/4885ABCB1 74/4885POLB 1690/4885
US-20050019251-A1 Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol FABP1, SLC35B2, SLC10A1 TDP1 3588/4885ABCB1 1244/4885POLB 485/4885
US-20220389046-A1 ANTICANCER COMPOUNDS MKI67, CCNI, API5 TDP1 2695/4885ABCB1 74/4885POLB 1690/4885
US-11084843-B2 Anticancer compounds MKI67, CCNI, API5 TDP1 2695/4885ABCB1 74/4885POLB 1690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.