SCHEMBL258998

SCHEMBL258998

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nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.68
ABCB1 P08183 1/20 0.41
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TSHR P16473 1/20 0.30
TRPV1 Q8NER1 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6464207 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL8117010 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL60323 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL8587285 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
SCHEMBL2279600 1.00 TDP1 (0.68) TDP1ABCB1POLBMAPK1ALDH1A1
Ammonia Solution, Strong SCHEMBL17061382 0.98 TDP1 (0.66) TDP1ABCB1POLBMAPK1
SCHEMBL60713 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL13893402 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL421756 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1
SCHEMBL426635 0.95 TDP1 (0.71) TDP1ABCB1POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192442-A Preparation method of GalNAc compound containing ribosyl ring 北京悦康科创医药科技股份有限公司 2025-06-24 CN claimed
CN-119613465-A Chemical synthesis method of haemophilus influenzae type b capsular polysaccharide derivative 江南大学 2025-03-14 CN claimed
CN-222566808-U Alcohol recovery device during tetra-acetyl ribose is refined 洛阳德胜生物科技股份有限公司 2025-03-07 CN claimed
US-12227534-B2 Method for preparing nicotinamide mononucleotide by using nicotinamide as raw material BONTAC BIO-ENGINEERING(SHENZHEN) CO., LTD. (CN) 2025-02-18 US claimed
CN-114717280-B Monopira Synthesis method of pyrrosia lingua 浙江工业大学 2024-12-20 CN claimed
CN-119119146-A New method for preparing 5-deoxidized triacetyl ribose 启东东岳药业有限公司 2024-12-13 CN claimed
CN-119039362-A Preparation method of beta-nicotinamide riboside chloride 广东肇庆星湖生物科技股份有限公司 2024-11-29 CN claimed
CN-118994269-A Preparation method of beta-nicotinamide mononucleotide 上海昶法新材料有限公司 2024-11-22 CN claimed
CN-116375772-B Preparation method and application of adenosine 北京先通国际医药科技股份有限公司 2024-11-01 CN claimed
US-20240247022-A1 A Process for Synthesis of Nicotinamide Riboside Chloride (NRCL) BOHAN & CO AS. (NO) 2024-07-25 US claimed
CN-111647032-A Synthesis method of beta-nicotinamide mononucleotide 上海舒泽生物科技研究所 2020-09-11 CN claimed
CN-108409818-B Method for synthesizing cytosine nucleoside 新乡拓新药业股份有限公司 2020-09-11 CN claimed
CN-111647033-A Method for preparing ribavirin by one-pot method 济南明鑫制药股份有限公司 2020-09-11 CN claimed
CN-109336937-B Preparation method of ribavirin 河南省科学院高新技术研究中心 2020-08-25 CN claimed
CN-111548383-A Process for preparing beta-nicotinamide mononucleotide 湖南和泰康瑞生物技术有限公司 2020-08-18 CN claimed
CN-111440170-A Method for synthesizing guanine by using guanosine 通辽德胜生物科技有限公司 2020-07-24 CN claimed
CN-111362944-A Method for synthesizing diacetylacyclovir by using guanosine 通辽德胜生物科技有限公司 2020-07-03 CN claimed
CN-111253448-A Preparation method and purification method of β -nicotinamide mononucleotide 上海昶法新材料有限公司 2020-06-09 CN claimed
CN-110642897-A Preparation method of beta-nicotinamide riboside chloride 武汉一若生物材料有限公司 2020-01-03 CN claimed
CN-106831916-B synthetic method of beta-thymidine 抚州市星辰药业有限公司 2019-12-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227534-B2 Method for preparing nicotinamide mononucleotide by using nicotinamide as raw material NADK, NUDT1, NAMPT TDP1 2571/4885ABCB1 2969/4885POLB 1120/4885
US-20240247022-A1 A Process for Synthesis of Nicotinamide Riboside Chloride (NRCL) NAMPT, NAPRT, NNT TDP1 3927/4885ABCB1 2956/4885POLB 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.