SCHEMBL22796963

SCHEMBL22796963

COc1cc2sccc2cc1[C@@H]1O[C@H](CO)[C@H](O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 17/20 0.56
SLC5A1 P13866 6/20 0.52
SELL P14151 1/20 0.46
SELP P16109 1/20 0.46
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22314236 0.82 SLC5A2 (0.59) SLC5A2SLC5A1SELLSELPACHE
SCHEMBL22314229 0.82 SLC5A2 (0.59) SLC5A2SLC5A1SELLSELPACHE
SCHEMBL26192723 0.82 SLC5A2 (0.59) SLC5A2SLC5A1SELLSELPACHE
SCHEMBL12426196 0.80 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL12662679 0.80 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL12426214 0.80 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL14049265 0.80 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL14049245 0.80 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL22796964 0.79 P2RY2 (0.59)
SCHEMBL1854535 0.76 SLC5A2 (0.75) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200392550-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS THE SCRIPPS RESEARCH INSTITUTE 2020-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200392550-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS RNGTT, MAX, POLRMT SLC5A2 4484/4885SLC5A1 4515/4885SELL 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.