Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22055729 | 0.91 | GAA (0.59) | ALDH1A1PIK3CDHPGDMAPK1GAA | |
| SCHEMBL5909217 | 0.91 | GAA (0.59) | ALDH1A1PIK3CDHPGDMAPK1GAA | |
| SCHEMBL26241740 | 0.83 | PIK3CD (0.52) | ALDH1A1PIK3CDHPGDMAPK1L3MBTL1 | |
| SCHEMBL18081171 | 0.83 | PIK3CD (0.52) | ALDH1A1PIK3CDHPGDMAPK1L3MBTL1 | |
| SCHEMBL18081188 | 0.82 | PIK3CD (0.51) | ALDH1A1PIK3CDHPGDMAPK1L3MBTL1 | |
| SCHEMBL1763339 | 0.82 | CHRNB2 (0.53) | ALDH1A1PIK3CDHPGDMAPK1GAA | |
| SCHEMBL1763337 | 0.82 | CHRNB2 (0.53) | ALDH1A1PIK3CDHPGDMAPK1GAA | |
| SCHEMBL26827492 | 0.81 | HTT (0.53) | ALDH1A1PIK3CDHPGDMAPK1L3MBTL1 | |
| SCHEMBL19454030 | 0.80 | HPGD (0.64) | HPGDMAPK1L3MBTL1GAALMNA | |
| SCHEMBL20009023 | 0.80 | PIK3CD (0.55) | ALDH1A1PIK3CDHPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252151-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. (US) | 2020-12-17 | — | — | WO | disclosed |