Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 3/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893492 | 0.86 | SLC40A1 (0.52) | GLO1SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL19799374 | 0.85 | MEN1 (0.51) | GLO1SLC40A1L3MBTL1IDO1MEN1 | |
| SCHEMBL20265625 | 0.82 | KDM4E (0.48) | GLO1SLC40A1KDM4EL3MBTL1MPI | |
| Hydrochloric Acid SCHEMBL20265677 | 0.81 | KDM4E (0.47) | GLO1SLC40A1KDM4EL3MBTL1MPI | |
| SCHEMBL14820067 | 0.80 | HTR1A (0.53) | GLO1SLC40A1KDM4EL3MBTL1IDO1 | |
| SCHEMBL15217626 | 0.79 | IDO1 (0.69) | KDM4EL3MBTL1MPIIDO1TDP1 | |
| SCHEMBL18484920 | 0.79 | SLC40A1 (0.49) | GLO1SLC40A1KDM4EL3MBTL1IDO1 | |
| SCHEMBL19990071 | 0.78 | KDM4E (0.70) | SLC40A1KDM4EL3MBTL1MPIIDO1 | |
| SCHEMBL20840563 | 0.76 | SLC40A1 (0.58) | GLO1SLC40A1KDM4EL3MBTL1MPI | |
| SCHEMBL15241122 | 0.76 | HTR1A (0.56) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252151-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. (US) | 2020-12-17 | — | — | WO | disclosed |