Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919359 | 0.89 | NAMPT (0.44) | CDK9ALDH1A1HTTNPC1MAPT | |
| SCHEMBL22797253 | 0.86 | PTPN2 (0.46) | EHMT2OXTRAVPR1ANPC1RAB9A | |
| SCHEMBL30012480 | 0.85 | EHMT2 (0.46) | EHMT2OXTRAVPR1ACDK9ALDH1A1 | |
| SCHEMBL25300699 | 0.85 | EHMT2 (0.46) | EHMT2OXTRAVPR1ACDK9ALDH1A1 | |
| SCHEMBL22671931 | 0.83 | IDH1 (0.40) | ALDH1A1HTTNPC1MAPTMAPK1 | |
| SCHEMBL29565939 | 0.83 | IDH1 (0.40) | ALDH1A1HTTNPC1MAPTMAPK1 | |
| SCHEMBL22797244 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HTTNPC1MAPTMAPK1 | |
| SCHEMBL22609210 | 0.82 | GAA (0.38) | ALDH1A1HTTMAPTKMT2ALMNA | |
| SCHEMBL22214268 | 0.81 | KMT2A (0.38) | EHMT2CDK9ALDH1A1HTTNPC1 | |
| SCHEMBL30728859 | 0.81 | KMT2A (0.38) | EHMT2CDK9ALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325896-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2022-05-10 | — | — | US | disclosed |
| US-11325896-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2022-05-10 | — | — | US | disclosed |
| US-20200392117-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392117-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM2, CHRM3, CHRM4 | EHMT2 561/4885OXTR 236/4885AVPR1A 287/4885 |
| US-11325896-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | CHRM2, CHRM3, CHRM5 | EHMT2 702/4885OXTR 218/4885AVPR1A 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.