Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22214268 | 1.00 | KMT2A (0.38) | KMT2ALMNAALDH1A1NPC1MAPT | |
| SCHEMBL29628212 | 1.00 | KMT2A (0.38) | KMT2ALMNAALDH1A1NPC1MAPT | |
| SCHEMBL25174104 | 0.87 | ALDH1A1 (0.34) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL29860367 | 0.87 | ALDH1A1 (0.34) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL29860167 | 0.87 | ALDH1A1 (0.34) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL22214205 | 0.86 | CDK9 (0.30) | KMT2ALMNAALDH1A1NPC1MAPT | |
| SCHEMBL22205446 | 0.84 | POLB (0.34) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL22205449 | 0.84 | POLB (0.34) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL23397596 | 0.84 | POLB (0.34) | KMT2ALMNAALDH1A1MAPTHTT | |
| SCHEMBL20705026 | 0.84 | POLB (0.34) | KMT2ALMNAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111194215-B | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-111499615-B | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2024-02-02 | — | — | CN | disclosed |