⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246831 | 0.97 | ALDH1A1 (0.42) | — | |
| SCHEMBL13497066 | 0.97 | ALDH1A1 (0.42) | — | |
| SCHEMBL16609955 | 0.97 | ALDH1A1 (0.42) | — | |
| SCHEMBL16609936 | 0.97 | ALDH1A1 (0.42) | — | |
| SCHEMBL651351 | 0.97 | ALDH1A1 (0.42) | — | |
| SCHEMBL1938094 | 0.94 | — | — | |
| SCHEMBL932523 | 0.88 | — | — | |
| SCHEMBL9876428 | 0.85 | — | — | |
| SCHEMBL11298532 | 0.83 | FFAR3 (0.39) | — | |
| SCHEMBL2154593 | 0.81 | CES2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779140-B | Compounds and methods for synthesizing 5- (N-protected tryptophanyl carboxamide) -2' -deoxyuridine phosphoramidites for incorporation into nucleic acid sequences | 私募蛋白质体操作有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-10634679-B2 | Compounds and methods for the synthesis of 5-(N-protected-tryptaminocarboxyamide)-2′-deoxyuridine phosphoramidite for incorporation into a nucleic acid | SOMALOGIC, INC. (US) | 2020-04-28 | — | — | US | claimed |
| EP-3430022-B1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDITE FOR INCORPORATION INTO A NUCLEIC ACID SEQUENCE | SOMALOGIC INC (US) | 2020-03-11 | — | — | EP | claimed |
| US-20190031702-A1 | Compounds and Methods for the Synthesis of 5-(N-Protected-Tryptaminocarboxyamide)-2'-Deoxyuridine Phosphoramidate for Incorporation into a Nucleic Sequence | SOMALOGIC, INC. (US) | 2019-01-31 | — | — | US | claimed |
| EP-3430022-A1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDATE FOR INCORPORATION INTO A NUCLEIC SEQUENCE | Somalogic, Inc. (US) | 2019-01-23 | — | — | EP | claimed |
| WO-2017160672-A1 | COMPOUNDS AND METHODS FOR THE SYNTHESIS OF 5-(N-PROTECTED-TRYPTAMINOCARBOXYAMIDE)-2'-DEOXYURIDINE PHOSPHORAMIDATE FOR INCORPORATION INTO A NUCLEIC SEQUENCE | SOMALOGIC, INC. (US) | 2017-09-21 | — | — | WO | claimed |
| US-12565494-B2 | Inhibitors of human respiratory syncytial virus and metapneumovirus | MERCK SHARP & DOHME LLC | 2026-03-03 | — | — | US | disclosed |
| EP-4522604-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | Merck Sharp & Dohme LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220225-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230365551-A1 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | US | disclosed |
| EP-3644990-B1 | 5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2022-11-30 | — | — | EP | disclosed |
| CN-108779140-B | Compounds and methods for synthesizing 5- (N-protected tryptophanyl carboxamide) -2' -deoxyuridine phosphoramidites for incorporation into nucleic acid sequences | 私募蛋白质体操作有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-10981902-B2 | 5-(pyridin-3-yl)oxazole allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2021-04-20 | — | — | US | disclosed |
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040157820-A1 | Porphyrin-metal complexes and oxygen infusions containing the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1422229-A1 | PORPHYRIN-METAL COMPLEXES AND OXYGEN INFUSIONS CONTAINING THE SAME | Japan Science and Technology Corporation (JP) | 2004-05-26 | — | — | EP | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |
| US-4969950-A | Triazole compounds and methods for regulating plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
| US-3959269-A | TRANQUILIZERS, SEDATIVES | SANDOZ, INC. (US) | 1976-05-25 | — | — | US | disclosed |