SCHEMBL2279792

SCHEMBL2279792

CCOCC(c1ccccc1)C(COCC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.46
TAAR1 Q96RJ0 2/20 0.43
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43
OPRK1 P41145 1/20 0.43
OPRL1 P41146 1/20 0.43
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
TACR1 P25103 2/20 0.37
MMP8 P22894 1/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1579917 0.90 TAAR1 (0.53) HKDC1TAAR1OPRM1OPRD1OPRK1
SCHEMBL12846951 0.90 TAAR1 (0.53) HKDC1TAAR1OPRM1OPRD1OPRK1
SCHEMBL8039538 0.86 TAAR1 (0.41) HKDC1TAAR1OPRM1OPRD1OPRK1
SCHEMBL1785539 0.82 SMN1; SMN2 (0.47) HKDC1TAAR1OPRM1OPRD1OPRK1
SCHEMBL16859925 0.80 MMP8 (0.49) TSHRMEN1KMT2ASMN1; SMN2SLC6A2
SCHEMBL19494268 0.80 HKDC1 (0.39) HKDC1TAAR1OPRM1OPRD1OPRK1
SCHEMBL1911339 0.80 SCN4A (0.59) TACR1
SCHEMBL56226 0.80 SCN4A (0.59) TACR1
SCHEMBL12846898 0.80 TAAR1 (0.50) TAAR1OPRM1OPRD1OPRK1OPRL1
SCHEMBL13195927 0.80 TAAR1 (0.50) TAAR1OPRM1OPRD1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1875961-B1 CAPSULAR FINE PARTICLE COMPRISING OLEFINIC POLYMER MITSUI CHEMICALS INC (JP) 2018-08-29 EP disclosed
US-8349451-B2 Capsular fine particle comprising olefinic polymer MITSUI CHEMICALS, INC. (JP) 2013-01-08 US disclosed
US-20110196103-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST MITSUI CHEMICALS, INC. (US) 2011-08-11 US disclosed
EP-1829900-B1 ETHYLENE POLYMER FINE PARTICLES, FUNCTIONAL GROUP-CONTAINING ETHYLENE POLYMER FINE PARTICLES, AND CATALYST CARRIER FOR PRODUCTION THEREOF MITSUI CHEMICALS INC (JP) 2010-08-18 EP disclosed
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7728078-B2 Blend of a polypropylene and a elastomeric copolymer of 60-90 mol % propylene units and 10- 40 mol % of 1-butene units; sheets and films with excellent flexibility and impact resistance as well as sufficient heat resistance and low-temperature heat-sealability MITSUI CHEMICALS, INC. (JP) 2010-06-01 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
US-7601423-B2 Ethylene-based polymer microparticles, functional group-containing ethylene-based polymer microparticles, and catalyst carriers for manufacture thereof MITSUI CHEMICALS, INC. (JP) 2009-10-13 US disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
CN-1052681-A The catalyst component of olefinic polymerization and catalyzer HIMONT INC (US) 1991-07-03 CN disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
EP-0423786-A2 Polymetallic catalysts, method of preparing and polymers produced thereby MONTELL NORTH AMERICA INC. (US) 1991-04-24 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
US-4971937-A COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS HIMONT INCORPORATED (US) 1990-11-20 US disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed
EP-0361494-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-04 EP disclosed