Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22814430 | 0.82 | USP2 (0.46) | USP2SMN1; SMN2GPR119RECQLALDH1A1 | |
| SCHEMBL22799174 | 0.76 | USP2 (0.47) | USP2SMN1; SMN2GPR119RECQLTSHR | |
| SCHEMBL22799096 | 0.74 | USP2 (0.41) | USP2SMN1; SMN2GPR119RECQLALDH1A1 | |
| SCHEMBL28804351 | 0.74 | USP2 (0.39) | USP2SMN1; SMN2GPR119RECQLALDH1A1 | |
| SCHEMBL29715682 | 0.74 | USP2 (0.39) | USP2SMN1; SMN2GPR119RECQLALDH1A1 | |
| SCHEMBL28804350 | 0.74 | USP2 (0.39) | USP2SMN1; SMN2GPR119RECQLALDH1A1 | |
| SCHEMBL156363 | 0.74 | USP2 (0.56) | USP2SMN1; SMN2GPR119RECQLHPGD | |
| SCHEMBL21843465 | 0.73 | USP2 (0.49) | USP2SMN1; SMN2GPR119RECQLMAPT | |
| SCHEMBL25357154 | 0.73 | USP2 (0.41) | USP2SMN1; SMN2GPR119ALDH1A1LMNA | |
| SCHEMBL4189009 | 0.72 | USP2 (0.50) | USP2SMN1; SMN2GPR119RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448923-B | Pyrimidine-fused ring compound, preparation method and application thereof | 上海青煜医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-110156786-B | Pyrimido-cyclic compounds, process for their preparation and their use | 青煜医药研发(上海)有限公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-3753941-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Blueray Biopharma Co., Ltd. (CN) | 2020-12-23 | — | — | EP | disclosed |