Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798992 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL22813793 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL19233819 | 0.87 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL22798572 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL22798571 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL22813769 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL1120408 | 0.74 | LMNA (0.46) | ALDH1A1MAPTHPGDTSHRKMT2A | |
| SCHEMBL22798889 | 0.73 | ALDH1A1 (0.70) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL12481284 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL22798772 | 0.72 | PDE4B (0.48) | ALDH1A1MAPTHPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753560-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD Pharma A/S (DK) | 2020-12-23 | — | — | EP | disclosed |