Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SLC1A5 | Q15758 | 8/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957565 | 0.81 | NOS3 (0.52) | NOS3NOS1NOS2MAPTSLC1A5 | |
| SCHEMBL31734855 | 0.79 | HPGD (0.53) | NOS3NOS1NOS2MAPTSLC1A5 | |
| SCHEMBL23069036 | 0.77 | NOS3 (0.56) | NOS3NOS1NOS2MAPTALPI | |
| SCHEMBL4595466 | 0.77 | NOS3 (0.55) | NOS3NOS1NOS2MAPTSLC1A5 | |
| SCHEMBL29750308 | 0.77 | NOS3 (0.55) | NOS3NOS1NOS2MAPTSLC1A5 | |
| SCHEMBL23069035 | 0.77 | NOS3 (0.56) | NOS3NOS1NOS2MAPTALPI | |
| SCHEMBL17347722 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2A | |
| SCHEMBL155235 | 0.77 | NOS3 (0.55) | NOS3NOS1NOS2MAPTSLC1A5 | |
| SCHEMBL155234 | 0.77 | NOS3 (0.55) | NOS3NOS1NOS2MAPTSLC1A5 | |
| SCHEMBL22444890 | 0.77 | NOS3 (0.47) | NOS3NOS1NOS2MAPTSLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338431-A1 | HUMAN HEPATOCYTES AND USES THEREOF | ACCELERATED BIOSCIENCES CORP. | 2023-10-26 | — | — | US | disclosed |
| US-20210330713-A1 | HUMAN HEPATOCYTES AND USES THEREOF | ACCELERATED BIOSCIENCES CORP. | 2021-10-28 | — | — | US | disclosed |
| CN-107208054-B | Induced hepatocytes and uses thereof | 艾克塞利瑞提德生物技术公司 | 2021-09-17 | — | — | CN | disclosed |
| US-11026979-B2 | Human hepatocytes and uses thereof | ACCELERATED BIOSCIENCES CORP. (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200345788-A1 | HUMAN HEPATOCYTES AND USES THEREOF | ACCELERATED BIOSCIENCES CORP. | 2020-11-05 | — | — | US | disclosed |
| US-10765704-B2 | Induced hepatocytes and uses thereof | ACCELERATED BIOSCIENCES CORP. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20180000868-A1 | Induced Hepatocytes and Uses Thereof | ACCELERATED BIOSCIENCES CORP. | 2018-01-04 | — | — | US | disclosed |
| US-9808490-B2 | Induced hepatocytes and uses thereof | ACCELERATED BIOSCIENCES CORP. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160199416-A1 | Induced Hepatocytes and Uses Thereof | ACCELERATED BIOSCIENCES CORP. | 2016-07-14 | — | — | US | disclosed |
| EP-2516454-A1 | MODIFIED BOVINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES | Ambrx, Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011087808-A1 | MODIFIED BOVINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES | AMBRX, INC. (US) | 2011-07-21 | — | — | WO | disclosed |