Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872624 | 0.86 | CXCL8 (0.49) | MAPTCXCL8L3MBTL1FABP4FABP5 | |
| SCHEMBL25123136 | 0.85 | CXCL8 (0.48) | MAPTCXCL8L3MBTL1FABP4FABP5 | |
| SCHEMBL29990992 | 0.85 | CXCL8 (0.48) | MAPTCXCL8L3MBTL1FABP4FABP5 | |
| SCHEMBL17347724 | 0.83 | MAPT (0.52) | MAPTL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL29387915 | 0.79 | LTB4R (0.56) | MAPTMEN1KMT2APTGER1PTGER4 | |
| SCHEMBL5808039 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2AMAOBNPC1 | |
| SCHEMBL31542585 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2AMAOBNPC1 | |
| SCHEMBL3700349 | 0.79 | CXCL8 (0.57) | MAPTCXCL8L3MBTL1FABP4FABP5 | |
| SCHEMBL503961 | 0.79 | L3MBTL1 (0.77) | CXCL8L3MBTL1FABP4FABP5AKR1B1 | |
| SCHEMBL11217443 | 0.77 | CXCL8 (0.60) | MAPTCXCL8L3MBTL1FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151919-B1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2023-08-30 | — | — | EP | disclosed |
| US-20210221835-A1 | CARBON-MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-07-22 | — | — | US | disclosed |
| US-10300069-B2 | Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| WO-2018093924-A1 | CARBON MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) | 2017-05-11 | — | — | US | disclosed |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) | 2017-05-11 | — | — | US | disclosed |
| WO-2015191616-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | MB, CYC1, COX15 | MAPT 3963/4885CXCL8 522/4885L3MBTL1 1953/4885 |
| US-20210221835-A1 | CARBON-MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | MB, HMOX1, CYC1 | MAPT 3633/4885CXCL8 292/4885L3MBTL1 2079/4885 |
| US-10300069-B2 | Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof | MB, CYC1, COX15 | MAPT 3963/4885CXCL8 522/4885L3MBTL1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.