SCHEMBL2280041

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12374001	0.90	SLC6A4 (0.38)	MEN1KMT2ANPC1RAB9AMAPT
	SCHEMBL12374006	0.89	LTA4H (0.38)	ALDH1A1BTK
	SCHEMBL12373975	0.88	HTT (0.42)	MEN1KMT2AMAPTKDM4EALDH1A1
	SCHEMBL2281618	0.88	LTA4H (0.39)	MEN1KMT2AMAPTNPBWR1MCHR1
	SCHEMBL12373991	0.86	ADORA1 (0.35)	KMT2AMAPTP2RX3
	SCHEMBL2277242	0.86	POLB (0.40)	MEN1KMT2ANPC1RAB9AMAPT
	SCHEMBL12374034	0.85	SMN1; SMN2 (0.36)	MEN1KMT2ARAB9AMAPTALDH1A1
	SCHEMBL12374054	0.82	LTA4H (0.48)	MEN1KMT2ANPC1RAB9AMAPT
	SCHEMBL12374028	0.82	TDP1 (0.31)	ALDH1A1TDP1
	SCHEMBL12374011	0.82	LNPEP (0.41)	MEN1KMT2ANPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.