Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22800179 | 0.94 | KDM4E (0.43) | KDM4EALDH1A1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL22800871 | 0.87 | ALDH1A1 (0.45) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL22800180 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL22800873 | 0.79 | JAK3 (0.33) | KDM4EMAPTCYP1A2HTTNPSR1 | |
| SCHEMBL22800284 | 0.78 | SLC6A3 (0.43) | KDM4EALDH1A1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL22800165 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1SLC6A3KMT2AMEN1 | |
| SCHEMBL22799654 | 0.74 | SLC6A3 (0.41) | KDM4EALDH1A1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL1586163 | 0.73 | SLC6A3 (0.54) | KDM4EALDH1A1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL22800160 | 0.73 | KDM4E (0.64) | KDM4EALDH1A1SLC6A3KMT2AMEN1 | |
| SCHEMBL28576991 | 0.72 | KDM4E (0.62) | KDM4EALDH1A1SLC6A3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | Knobbe, Martens, Olson & Bear, LLP | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN2, CAPN1 | KDM4E 1957/4885ALDH1A1 3918/4885SLC6A3 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.