Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RRM1 | P23921 | 2/20 | 0.50 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801111 | 0.88 | KDM4E (0.53) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL22801049 | 0.85 | SCD (0.51) | KDM4EKMT2AMAPTMEN1HTT | |
| SCHEMBL22801093 | 0.82 | KDM4E (0.52) | KDM4EKMT2AMAPTMEN1HTT | |
| SCHEMBL22801120 | 0.82 | MAPT (0.53) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL22801037 | 0.81 | ALDH1A1 (0.50) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL12248866 | 0.80 | KDM4E (0.69) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL5731231 | 0.80 | KDM4E (0.69) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL2754074 | 0.80 | KDM4E (0.78) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL22822367 | 0.79 | KDM4E (0.51) | KDM4EKMT2AATMMAPTMEN1 | |
| SCHEMBL12249036 | 0.79 | KDM4E (0.70) | KDM4EKMT2AATMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | NATIONAL INSTITUTES OF HEALTH | 2020-12-24 | — | — | US | disclosed |
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | NATIONAL INSTITUTES OF HEALTH | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | MAVS, ZC3HAV1, EIF2AK2 | KDM4E 453/4885KMT2A 2006/4885ATM 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.