Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801201 | 0.91 | TAAR1 (0.42) | TAAR1AOC3IDO1ALOX5MBTPS1 | |
| SCHEMBL31289110 | 0.91 | TAAR1 (0.42) | TAAR1AOC3IDO1ALOX5MBTPS1 | |
| SCHEMBL21178203 | 0.84 | IDO1 (0.46) | TAAR1AOC3IDO1SLC6A2SLC6A3 | |
| SCHEMBL22801250 | 0.83 | KDM4E (0.34) | TAAR1SLC6A2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL22801234 | 0.82 | IDO1 (0.39) | IDO1SLC6A2SLC6A3MAOBALDH1A1 | |
| SCHEMBL21178001 | 0.77 | CA1 (0.41) | TAAR1AOC3IDO1MEN1KMT2A | |
| SCHEMBL22801232 | 0.74 | TAAR1 (0.42) | TAAR1AOC3SLC6A2SLC6A3MAOB | |
| SCHEMBL22801238 | 0.73 | TAAR1 (0.32) | TAAR1 | |
| SCHEMBL22801251 | 0.73 | TAAR1 (0.47) | TAAR1IDO1ALOX5SLC6A2SLC6A3 | |
| SCHEMBL21178741 | 0.72 | KDM4E (0.36) | TAAR1SLC6A2ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425542-A1 | CYCLIC DEOXYRIBONUCLEOTIDE COMPOUNDS | NUCORION PHARMACEUTICALS INC (US) | 2024-12-26 | — | — | US | disclosed |
| US-12110311-B2 | Cyclic deoxyribonucleotide compounds | NUCORION PHARMACEUTICALS, INC. (US) | 2024-10-08 | — | — | US | disclosed |
| US-20220298199-A1 | CYCLIC DEOXYRIBONUCLEOTIDE COMPOUNDS | NUCORION PHARMACEUTICALS, INC. | 2022-09-22 | — | — | US | disclosed |
| US-11427550-B2 | 5-fluorouracil compounds | NUCORION PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| EP-3999519-A1 | CYCLIC DEOXYRIBONUCLEOTIDE COMPOUNDS | NUCORION PHARMACEUTICALS, INC. (US) | 2022-05-25 | — | — | EP | disclosed |
| WO-2021011692-A1 | CYCLIC DEOXYRIBONUCLEOTIDE COMPOUNDS | NUCORION PHARMACEUTICALS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298199-A1 | CYCLIC DEOXYRIBONUCLEOTIDE COMPOUNDS | DPYD, TYMP, TYMS | TAAR1 4404/4885AOC3 3016/4885IDO1 3984/4885 |
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | DPYD, DHFR, FAU | TAAR1 4315/4885AOC3 2720/4885IDO1 4055/4885 |
| US-20240425542-A1 | CYCLIC DEOXYRIBONUCLEOTIDE COMPOUNDS | DPYD, TYMP, TYMS | TAAR1 4404/4885AOC3 3016/4885IDO1 3984/4885 |
| US-12110311-B2 | Cyclic deoxyribonucleotide compounds | DPYD, TYMP, TYMS | TAAR1 4404/4885AOC3 3016/4885IDO1 3984/4885 |
| US-11427550-B2 | 5-fluorouracil compounds | DPYD, DHFR, MTHFD1 | TAAR1 3838/4885AOC3 1560/4885IDO1 3948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.