SCHEMBL22801902

SCHEMBL22801902

C1=CC2(CCc3ccccc3O2)Oc2ccc3ccccc3c21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
HPGD P15428 3/20 0.47
GLA P06280 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
ADRA1D P25100 2/20 0.41
ADRA1A P35348 2/20 0.41
ADRA1B P35368 2/20 0.41
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
SIGMAR1 Q99720 1/20 0.34
HSD17B10 Q99714 2/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22801883 0.87 KDM4E (0.43) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL30612735 0.73 ALDH1A1 (0.55) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL5913910 0.73 ALDH1A1 (0.55) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL30284405 0.71 KDM4E (0.50) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL361847 0.71 KDM4E (0.50) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL15196166 0.70 ALDH1A1 (0.52) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL6140044 0.69 KDM4E (0.49) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL13326505 0.69 KDM4E (0.49) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL6139999 0.69 ALDH1A1 (0.51) KDM4EHPGDGLAALDH1A1MEN1
SCHEMBL30612751 0.69 ALDH1A1 (0.51) KDM4EHPGDGLAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323595-A1 WATER-SOLUBLE FILM BASED DELIVERY SYSTEMS FOR COLORANTS, GLITTER, AND OTHER CHEMISTRIES CRAYOLA LLC (US) 2023-10-12 US disclosed
US-20230323051-A1 WATER-SOLUBLE FILM BASED DELIVERY SYSTEMS FOR COLORANTS, GLITTER, AND OTHER ARTISTIC EFFECTS CRAYOLA LLC (US) 2023-10-12 US disclosed
US-11746235-B2 Two part silicone moldable eraser CRAYOLA LLC (US) 2023-09-05 US disclosed
US-20200399472-A1 TWO PART SILICONE MOLDABLE ERASER CRAYOLA LLC (US) 2020-12-24 US disclosed