Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18210515 | 0.77 | MYC (0.36) | PARP1RAB9AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2283018 | 0.75 | NPC1 (0.44) | PARP1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL22396471 | 0.70 | MYC (0.50) | KDM4EALDH1A1MAPTMYCSMN1; SMN2 | |
| SCHEMBL3806342 | 0.69 | NR1H2 (0.36) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7680902 | 0.69 | BCAT2 (0.40) | PARP1RAB9ANPC1AURKA | |
| SCHEMBL7680894 | 0.69 | BCAT2 (0.50) | PARP1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL883905 | 0.68 | KMT2A (0.58) | PARP1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL4538970 | 0.68 | EPHX2 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL353774 | 0.68 | AURKA (0.60) | PARP1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30945091 | 0.68 | EPHX2 (0.52) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746439-A2 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2020-12-09 | — | — | EP | claimed |
| WO-2019150219-A2 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2019-08-08 | — | — | WO | claimed |
| WO-2013009830-A1 | METHODS OF TREATMENT | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | WO | claimed |
| WO-2013009810-A1 | METHODS OF TREATMENT | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | WO | claimed |
| WO-2011088181-A9 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| WO-2013009810-A1 | METHODS OF TREATMENT | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | WO | disclosed |
| WO-2013009830-A1 | METHODS OF TREATMENT | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | WO | disclosed |
| EP-2533783-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |