Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22803403 | 0.88 | DGAT1 (0.40) | DGAT1HSP90AB1MMP2MMP9MMP8 | |
| SCHEMBL18751726 | 0.87 | DGAT1 (0.48) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL20694373 | 0.85 | HSP90AB1 (0.41) | DGAT1HSP90AB1MMP2MMP9MMP8 | |
| SCHEMBL18751731 | 0.84 | DGAT1 (0.53) | DGAT1HSP90AB1MMP2MMP9MMP8 | |
| SCHEMBL22803402 | 0.83 | HSP90AB1 (0.40) | DGAT1HSP90AB1MMP2MMP9MMP8 | |
| SCHEMBL21118065 | 0.83 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL21100148 | 0.83 | DGAT1 (0.44) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL20999887 | 0.83 | DGAT1 (0.44) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL19704939 | 0.83 | DGAT1 (0.44) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21118070 | 0.81 | DGAT1 (0.54) | DGAT1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390895-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390895-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | CD47, MCL1, BCL9 | DGAT1 1956/4885HSP90AB1 639/4885MMP2 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.