Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694373 | 0.87 | HSP90AB1 (0.41) | HSP90AB1DGAT1ALOX5MMP2MMP9 | |
| SCHEMBL21087467 | 0.83 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL22803422 | 0.83 | DGAT1 (0.41) | HSP90AB1DGAT1MMP2MMP9MMP8 | |
| SCHEMBL9889273 | 0.82 | HSP90AB1 (0.40) | HSP90AB1DGAT1ALOX5MMP2MMP9 | |
| SCHEMBL19704939 | 0.81 | DGAT1 (0.44) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL24702107 | 0.80 | HDAC1 (0.40) | HDAC1FFAR1 | |
| SCHEMBL20257915 | 0.80 | HSP90AB1 (0.40) | HSP90AB1DGAT1 | |
| SCHEMBL21087029 | 0.80 | DGAT1 (0.55) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL19652940 | 0.79 | HSP90AB1 (0.49) | HSP90AB1DGAT1 | |
| SCHEMBL23974499 | 0.78 | HDAC1 (0.43) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390895-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390895-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | CD47, MCL1, BCL9 | HSP90AB1 639/4885DGAT1 1956/4885ALOX5 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.