Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578149 | 0.91 | GRM5 (0.58) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1579128 | 0.86 | GRM5 (0.54) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1578303 | 0.85 | FAAH (0.62) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1578460 | 0.84 | GRM5 (0.54) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1578601 | 0.83 | GRM5 (0.54) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1578628 | 0.83 | GRM5 (0.71) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1578956 | 0.83 | GRM5 (0.52) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL2638308 | 0.83 | PABPC1 (0.65) | RAB9AKDM4EMAPTAGTR1OPRK1 | |
| SCHEMBL9914297 | 0.83 | PBK (0.55) | GRM5RAB9AKDM4EMAPTAGTR1 | |
| SCHEMBL1578147 | 0.83 | PBK (0.55) | GRM5RAB9AKDM4EMAPTAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | disclosed |