Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820718 | 0.91 | ADORA1 (0.58) | ADORA1ADORA2A | |
| SCHEMBL12915446 | 0.87 | MEN1 (0.59) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL13045285 | 0.85 | MEN1 (0.56) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL13045288 | 0.83 | MEN1 (0.54) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL22824545 | 0.82 | BCHE (0.48) | ADORA1ADORA2ARAB9A | |
| SCHEMBL13045287 | 0.81 | MEN1 (0.52) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL9611715 | 0.80 | RAB9A (0.60) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL13045291 | 0.78 | MEN1 (0.48) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL13045286 | 0.78 | MEN1 (0.48) | ADORA1ADORA2AMEN1RAB9AKMT2A | |
| SCHEMBL7509409 | 0.78 | CCR1 (0.58) | RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272417-B | 2-methyl-1, 8-naphthyridine compound and preparation method and application thereof | 五邑大学 | 2021-07-13 | — | — | CN | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |
| CN-110272417-A | 2- methyl-1,8- naphthyridine type compound and the preparation method and application thereof | 五邑大学 | 2019-09-24 | — | — | CN | disclosed |