Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 8/20 | 0.43 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | ZAP70 | P43403 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13734821 | 0.79 | RAB9A (0.50) | RAB9AHSP90AA1SPHK2SPHK1SYK | |
| SCHEMBL8673384 | 0.78 | RAB9A (0.63) | RAB9AHSP90AA1SYKSRCZAP70 | |
| SCHEMBL9287533 | 0.77 | CCR1 (0.54) | RAB9AHSP90AA1SPHK2SPHK1SYK | |
| SCHEMBL25233346 | 0.72 | HSP90AA1 (0.62) | RAB9AHSP90AA1SPHK2SPHK1SYK | |
| SCHEMBL7509409 | 0.71 | CCR1 (0.58) | RAB9A | |
| SCHEMBL4902877 | 0.70 | RAB9A (0.61) | RAB9AHSP90AA1SYKSRCZAP70 | |
| SCHEMBL5792282 | 0.69 | RAB9A (1.00) | RAB9AHSP90AA1SYKPDPK1 | |
| SCHEMBL13830917 | 0.69 | RAB9A (0.44) | RAB9AHSP90AA1SPHK2SPHK1SYK | |
| SCHEMBL10092529 | 0.68 | CCR1 (0.56) | RAB9AHSP90AA1SPHK2SPHK1SYK | |
| SCHEMBL22804146 | 0.68 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272417-B | 2-methyl-1, 8-naphthyridine compound and preparation method and application thereof | 五邑大学 | 2021-07-13 | — | — | CN | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |