Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 4/20 | 0.60 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.54 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523476 | 0.84 | PLOD2 (0.69) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL29623599 | 0.83 | PLOD2 (0.55) | PLOD2PLOD3PLOD1SMN1; SMN2MAPT | |
| SCHEMBL10613054 | 0.83 | PLOD2 (0.67) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL9565951 | 0.83 | PLOD2 (0.67) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL30846025 | 0.83 | PLOD2 (0.67) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL9630807 | 0.83 | PLOD2 (0.67) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL9654173 | 0.83 | PLOD2 (0.67) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL6666160 | 0.81 | PLOD2 (0.66) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| Dimethylamine SCHEMBL10398768 | 0.80 | PLOD2 (0.62) | PLOD2PLOD3PLOD1CES1SMN1; SMN2 | |
| SCHEMBL31211553 | 0.78 | CES1 (0.67) | CES1CYP3A4MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986875-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020254490-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-24 | — | — | WO | disclosed |