Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.50 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718057 | 0.91 | PLOD2 (0.66) | PLOD2NPC1RAB9AMAPTLMNA | |
| SCHEMBL22805019 | 0.83 | PLOD2 (0.60) | PLOD2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL976028 | 0.77 | RAB9A (0.68) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL313164 | 0.77 | PLOD2 (0.70) | PLOD2MAPTALDH1A1PLOD3PLOD1 | |
| SCHEMBL450084 | 0.77 | RAB9A (0.85) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL782256 | 0.76 | NR1H4 (0.49) | PLOD2NPC1RAB9AMAPTLMNA | |
| SCHEMBL4588764 | 0.74 | PLOD2 (0.66) | PLOD2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL1593867 | 0.74 | PLOD2 (0.70) | PLOD2NPC1RAB9AMAPTLMNA | |
| SCHEMBL1177177 | 0.73 | RAB9A (0.72) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL19888140 | 0.73 | CA1 (0.57) | NPC1MAPTLMNAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986875-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |