Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997004 | 0.85 | PTGS2 (0.50) | PTGS2S1PR1PTGS1 | |
| SCHEMBL22828096 | 0.77 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL3451851 | 0.77 | PTGS2 (0.65) | PTGS2MEN1MAPTKMT2AMCOLN3 | |
| SCHEMBL3152021 | 0.76 | PTGS2 (0.48) | PTGS2MEN1KMT2APTGS1 | |
| SCHEMBL4411696 | 0.75 | S1PR1 (0.52) | PTGS2S1PR1MEN1KMT2ALMNA | |
| SCHEMBL123239 | 0.75 | PTGS2 (0.43) | PTGS2KDM1A | |
| SCHEMBL7375735 | 0.74 | LMNA (0.57) | PTGS2MEN1MAPTKMT2ALMNA | |
| SCHEMBL22827970 | 0.74 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL5309273 | 0.74 | KDM1A (0.49) | PTGS2KDM1APTGS1 | |
| SCHEMBL21469881 | 0.73 | PTGS2 (0.41) | PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106275-A1 | RADIOLABELED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-04-07 | — | — | US | disclosed |
| WO-2020257653-A1 | RADIOLABELED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106275-A1 | RADIOLABELED COMPOUNDS AND USES THEREOF | PAICS, TMEM14C, SLCO1B1 | PTGS2 4365/4885S1PR1 896/4885MEN1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.