Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22807658 | 0.90 | GLP1R (0.43) | HPGDHTTSMN1; SMN2GLP1RAKT1 | |
| SCHEMBL22807673 | 0.89 | GLP1R (0.37) | HPGDHTTSMN1; SMN2GLP1RKLK7 | |
| SCHEMBL24202346 | 0.88 | GLP1R (0.51) | HPGDHTTSMN1; SMN2GLP1RAKT1 | |
| SCHEMBL20842936 | 0.84 | SMN1; SMN2 (0.43) | HPGDHTTSMN1; SMN2GLP1RHDAC1 | |
| SCHEMBL31235843 | 0.84 | GLP1R (0.35) | GLP1RAKT1MEN1KMT2APOLB | |
| SCHEMBL22688292 | 0.83 | AKT1 (0.46) | AKT1KLK7KLK5HDAC1HDAC8 | |
| SCHEMBL3661271 | 0.81 | HDAC8 (0.42) | HPGDHTTSMN1; SMN2KLK7KLK5 | |
| SCHEMBL3661274 | 0.81 | HDAC8 (0.42) | HPGDHTTSMN1; SMN2KLK7KLK5 | |
| SCHEMBL31721990 | 0.79 | AKT1 (0.51) | GLP1RAKT1HDAC1HDAC8SIRT5 | |
| SCHEMBL22389051 | 0.79 | SMN1; SMN2 (0.39) | HPGDHTTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459546-B1 | MULTI-ARM POLYMERIC TARGETING ANTI-CANCER CONJUGATE | BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) | 2022-01-19 | — | — | EP | disclosed |
| US-10869863-B2 | Multi-arm polymeric targeting anti-cancer conjugate | BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2020-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10869863-B2 | Multi-arm polymeric targeting anti-cancer conjugate | TOP2A, TOP1, ABCG2 | HPGD 4151/4885HTT 3937/4885SMN1; SMN2 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.