Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24202346 | 0.93 | GLP1R (0.51) | GLP1RAKT1HPGDHTTSMN1; SMN2 | |
| SCHEMBL22807637 | 0.90 | HPGD (0.40) | GLP1RAKT1HPGDHTTSMN1; SMN2 | |
| SCHEMBL15096516 | 0.84 | POLB (0.45) | AKT1HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL31721990 | 0.84 | AKT1 (0.51) | GLP1RAKT1HDAC1HDAC8SIRT2 | |
| SCHEMBL19384704 | 0.81 | HPGD (0.47) | AKT1HPGDHTTSMN1; SMN2HDAC1 | |
| SCHEMBL19384786 | 0.81 | HPGD (0.47) | AKT1HPGDHTTSMN1; SMN2HDAC1 | |
| SCHEMBL18798881 | 0.81 | TDP1 (0.42) | GLP1RMEN1KMT2APOLBNPSR1 | |
| SCHEMBL16924988 | 0.81 | TDP1 (0.42) | GLP1RMEN1KMT2APOLBNPSR1 | |
| SCHEMBL18942764 | 0.81 | AKT1 (0.52) | AKT1HPGDHTTSMN1; SMN2HDAC1 | |
| SCHEMBL25133970 | 0.80 | PLK1 (0.46) | AKT1HPGDHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869863-B2 | Multi-arm polymeric targeting anti-cancer conjugate | BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2020-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10869863-B2 | Multi-arm polymeric targeting anti-cancer conjugate | TOP2A, TOP1, ABCG2 | GLP1R 3412/4885AKT1 928/4885HPGD 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.