Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711535 | 0.72 | PNMT (0.31) | — | |
| SCHEMBL14692605 | 0.71 | PTGS1 (0.39) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL11980220 | 0.71 | PTGS1 (0.39) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL2562180 | 0.66 | PTGS1 (0.39) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL17148355 | 0.65 | APP (0.38) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL12711542 | 0.64 | — | — | |
| SCHEMBL15979463 | 0.62 | PTGS1 (0.40) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL12788790 | 0.61 | MEN1 (0.36) | — | |
| SCHEMBL14645953 | 0.59 | PTGS1 (0.32) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL13859021 | 0.58 | ALDH1A1 (0.37) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870655-B2 | Indacen-4-one derivatives, process for their preparation and polymers containing them | ENI S.P.A. (IT) | 2020-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870655-B2 | Indacen-4-one derivatives, process for their preparation and polymers containing them | CORO1C, INTS9, C5 | PTGS1 1363/4885PTGS2 992/4885KDM4E 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.