Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MLYCD | O95822 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880072 | 0.82 | ALDH1A1 (0.73) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL20086461 | 0.82 | ALDH1A1 (0.60) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL22199591 | 0.79 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL18896262 | 0.79 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL7278525 | 0.79 | ALDH1A1 (0.71) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL14254805 | 0.79 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL20086467 | 0.79 | NPSR1 (0.58) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL26884995 | 0.78 | ALDH1A1 (0.55) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL3093916 | 0.78 | HSD17B10 (0.66) | ALDH1A1RAB9ANPSR1HTTHPGD | |
| SCHEMBL5201567 | 0.78 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPSR1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869934-B2 | Antiproliferative compounds and conjugates made therefrom | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10869934-B2 | Antiproliferative compounds and conjugates made therefrom | MKI67, HDGF, PCLAF | ALDH1A1 314/4885RAB9A 3108/4885NPSR1 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.